Looks like yes. I just upgraded to Big Sur 11.4 on a box with a config profile set to allow the extension, and the extension was approved automatically. I _did_ receive a notification explaining that Netskope could proxy traffic or some such, but wit...

Apple's MDM provides a way for administrators to "pre-approve" extensions through configuration profiles. Here's a link to a JamfNation discussion where a user details the Team ID and allowed system extensions for Netskope.