Looks like yes. I just upgraded to Big Sur 11.4 on a box with a config
profile set to allow the extension, and the extension was approved
automatically. I _did_ receive a notification explaining that Netskope
could proxy traffic or some such, but wit...
Apple's MDM provides a way for administrators to "pre-approve"
extensions through configuration profiles. Here's a link to a JamfNation
discussion where a user details the Team ID and allowed system
extensions for Netskope.